3-FPM (also known as 3-Fluorophenmetrazine, 3-FPH and PAL-593) is a designer drug, a phenylmorpholine-based stimulant and fluorinated analogue of phenmetrazine. 3-FPM (3-Fluorophenmetrazine, 3-FPH, PAL-593) acts as a norepinephrine-dopamine releasing agent. 3-FPM amphetamine is derivatives such as for example also 2-FMA or 4-FA.
Evaluation of its metabolic pathway revealed N‐oxidation, aryl hydroxylation and subsequent O‐methylation, alkyl hydroxylation, oxidation, and degradation of the ethyl‐bridge yielding the O/N‐bis‐dealkylated metabolite, combinations thereof and further glucuronidation or sulfations.
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